ACTION Registry

ACTION PHTS VADs before Transplant

Impact Of Ventricular Assist Device Use On Pediatric Heart Transplant Outcomes In A Linked Cohort Of The Advanced Cardiac Therapies Improving Outcomes Network (ACTION) And Pediatric Heart Transplant Society (PHTS) Databases

ACTION Publication, Publications

Children bridged to heart transplant on a ventricular assist device did not have worse graft survival than those supported medically. Drawing on 1,360 linked records from ACTION & PHTS, the study found that apparent differences between device types faded once patient complexity was accounted for.

Impact Of Ventricular Assist Device Use On Pediatric Heart Transplant Outcomes In A Linked Cohort Of The Advanced Cardiac Therapies Improving Outcomes Network (ACTION) And Pediatric Heart Transplant Society (PHTS) Databases Read More »

Survival comparison for renal replacement therapy in pediatric VAD patients versus those not on therapy, over one year.

Outcomes of ventricular assist device placement in pediatric patients with renal dysfunction requiring dialysis: an ACTION registry analysis

ACTION Publication, Publications

Children who needed renal replacement therapy at the time of VAD implantation were rare, sicker, and had lower one-year survival than other VAD patients. But after accounting for other factors, the therapy itself was not independently linked to mortality.

Outcomes of ventricular assist device placement in pediatric patients with renal dysfunction requiring dialysis: an ACTION registry analysis Read More »

RVAD timing in pediatric BiVAD support

Does Earlier Right Ventricular Assist Device Implant Confer a Survival Advantage

ACTION Publication, Publications

Concerns about survival have made biventricular support less common in children. Drawing on 223 pediatric patients in the ACTION registry, this study asked whether the timing of RVAD placement matters. Patients who received both devices in a single operation had better one-year survival, despite being sicker going into surgery.

Does Earlier Right Ventricular Assist Device Implant Confer a Survival Advantage Read More »

Infectious Adverse Events in Pediatric Paracorporeal Ventricular Assist Devices: An Analysis of the Advanced Cardiac Therapies Improving Outcomes Network (ACTION) Registry

ACTION Publication, Publications

This ACTION registry study of 812 children on paracorporeal VADs found that one-third experienced infectious adverse events, which were associated with worse survival. Overlapping device support and smaller body size emerged as independent risk factors for infection.

Infectious Adverse Events in Pediatric Paracorporeal Ventricular Assist Devices: An Analysis of the Advanced Cardiac Therapies Improving Outcomes Network (ACTION) Registry Read More »

HeartMate 3 in Pediatric and Complex Populations: Physiologic Rationale, Patient Selection, and Management Strategies

ACTION Publication, Publications

This review outlines the physiologic principles, patient selection criteria, and specialized management strategies needed to safely use the adult-designed HeartMate 3 heart pump in children, small adults, and patients with congenital heart disease or muscular dystrophy.

HeartMate 3 in Pediatric and Complex Populations: Physiologic Rationale, Patient Selection, and Management Strategies Read More »

The Advanced Cardiac Therapies Improving Outcomes Network (ACTION): A Multicenter Registry and Learning Health System for Pediatric and Congenital Heart Disease Associated Heart Failure

ACTION Publication, Publications

ACTION is a multicenter learning health system spanning 52 sites and over 5,000 pediatric patients that combines standardized data collection, quality improvement, and research to drive measurable gains in outcomes for children with congenital heart disease-related heart failure.

The Advanced Cardiac Therapies Improving Outcomes Network (ACTION): A Multicenter Registry and Learning Health System for Pediatric and Congenital Heart Disease Associated Heart Failure Read More »

The Pulse eNewsletter November 2025

The Pulse — Nov 2025

News, The Pulse

Happy Fall to All! We have many exciting updates to share, such as new pediatric Impella education materials for Providers and Patients/Families, a debrief of our incredibly successful first VAD Bootcamp, and many new publications and other tools. As we move into the holiday season, we reflect on our continued appreciation and thankfulness for the engagement and collaboration from all stakeholders that continue to excel our research, quality improvement, education, and advocacy efforts.

The Pulse — Nov 2025 Read More »