Heart of ACTION

Prospective Multicenter Evaluation of a Novel Active Driving System for Pediatric Ventricular Assist Device Support
This multicenter analysis shows bivalirudin is an effective alternative to heparin for anticoagulation in pediatric mechanical circulatory support, with comparable bleeding and stroke outcomes.
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Prospective Multicenter Evaluation of a Novel Active Driving System for Pediatric Ventricular Assist Device Support
This multicenter analysis shows bivalirudin is an effective alternative to heparin for anticoagulation in pediatric mechanical circulatory support, with comparable bleeding and stroke outcomes.

The Pulse — March 2026
We hope to see you soon! This special edition of The Pulse is focused on upcoming in-person meetings for the Spring and Summer! We hope to see you at any or all of these exciting events.

Multicenter Registry Analysis of Bivalirudin for Primary Anticoagulation in Pediatric HeartMate 3 Recipients: ACTION Analysis
This multicenter analysis shows bivalirudin is an effective alternative to heparin for anticoagulation in pediatric mechanical circulatory support, with comparable bleeding and stroke outcomes.

Meeting Report: Expanding Access to Advanced Cardiac Therapies, Including Ventricular Assist Devices (VADs) and Heart Transplantation in Muscular Dystrophy
Following a 2024 expert convening, a comprehensive clinical protocol was created to support VAD and transplant candidacy in Duchenne muscular dystrophy, translating consensus into real-world implementation.

Double Bridge to Heart Transplantation: Outcomes of Early vs Delayed Extra Corporeal Membrane Oxygenator Crossover in Pediatric Population
This study evaluates the progression of the distal aorta in patients with acute type A aortic dissection complicated by malperfusion syndrome who were treated with endovascular fenestration/stenting followed by delayed open aortic repair, finding that although these patients had faster distal aortic growth, their long-term survival and reoperation rates were similar to those without malperfusion syndrome.
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