Heart of ACTION

Explantation Of Durable Ventricular Assist Device For Myocardial Functional Recovery In Children: A Report From The ACTION Registry
A multi-center ACTION registry study found that while VAD removal following heart recovery is rare in children (about 3%), nearly three-quarters of those who underwent explantation remained alive without needing a transplant or new device at two-year follow-up.
Latest Highlights

Explantation Of Durable Ventricular Assist Device For Myocardial Functional Recovery In Children: A Report From The ACTION Registry
A multi-center ACTION registry study found that while VAD removal following heart recovery is rare in children (about 3%), nearly three-quarters of those who underwent explantation remained alive without needing a transplant or new device at two-year follow-up.

Prospective Multicenter Evaluation of a Novel Active Driving System for Pediatric Ventricular Assist Device Support
This multicenter analysis shows bivalirudin is an effective alternative to heparin for anticoagulation in pediatric mechanical circulatory support, with comparable bleeding and stroke outcomes.

The Pulse — March 2026
We hope to see you soon! This special edition of The Pulse is focused on upcoming in-person meetings for the Spring and Summer! We hope to see you at any or all of these exciting events.

Multicenter Registry Analysis of Bivalirudin for Primary Anticoagulation in Pediatric HeartMate 3 Recipients: ACTION Analysis
This multicenter analysis shows bivalirudin is an effective alternative to heparin for anticoagulation in pediatric mechanical circulatory support, with comparable bleeding and stroke outcomes.

Meeting Report: Expanding Access to Advanced Cardiac Therapies, Including Ventricular Assist Devices (VADs) and Heart Transplantation in Muscular Dystrophy
Following a 2024 expert convening, a comprehensive clinical protocol was created to support VAD and transplant candidacy in Duchenne muscular dystrophy, translating consensus into real-world implementation.
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