K.S.

ACTION PHTS VADs before Transplant

Impact Of Ventricular Assist Device Use On Pediatric Heart Transplant Outcomes In A Linked Cohort Of The Advanced Cardiac Therapies Improving Outcomes Network (ACTION) And Pediatric Heart Transplant Society (PHTS) Databases

ACTION Publication, Publications

Children bridged to heart transplant on a ventricular assist device did not have worse graft survival than those supported medically. Drawing on 1,360 linked records from ACTION & PHTS, the study found that apparent differences between device types faded once patient complexity was accounted for.

Impact Of Ventricular Assist Device Use On Pediatric Heart Transplant Outcomes In A Linked Cohort Of The Advanced Cardiac Therapies Improving Outcomes Network (ACTION) And Pediatric Heart Transplant Society (PHTS) Databases Read More »

The Pulse eNewsletter September 2026

The Pulse — September 2026

News, The Pulse

Happy Fall from ACTION! This edition of The Pulse covers a $910,000 Department of Defense award for Duchenne muscular dystrophy cardiac research, the relaunch of our VADs In Real Life (IRL) education series, ACTION at AHA Scientific Sessions 2026, new Harmonized Protocols and ACT-ONC resources, seven new publications, member spotlights, and open positions across ACTION centers.

The Pulse — September 2026 Read More »

Survival comparison for renal replacement therapy in pediatric VAD patients versus those not on therapy, over one year.

Outcomes of ventricular assist device placement in pediatric patients with renal dysfunction requiring dialysis: an ACTION registry analysis

ACTION Publication, Publications

Children who needed renal replacement therapy at the time of VAD implantation were rare, sicker, and had lower one-year survival than other VAD patients. But after accounting for other factors, the therapy itself was not independently linked to mortality.

Outcomes of ventricular assist device placement in pediatric patients with renal dysfunction requiring dialysis: an ACTION registry analysis Read More »

Comparison of pediatric VAD infection rates by device type: implanted, durable external, and temporary external.

Prevalence and Risk Factors for Ventricular Assist Device-Associated Infection in Children: An Analysis ACTION Study

ACTION Publication, Publications

About one in ten children supported by a ventricular assist device developed a device-associated infection, and one-year survival was no different for those who did. Drawing on 1,527 patients in the ACTION registry, the study found that implanted devices carried a proportionately higher infection rate than external ones.

Prevalence and Risk Factors for Ventricular Assist Device-Associated Infection in Children: An Analysis ACTION Study Read More »

RVAD timing in pediatric BiVAD support

Does Earlier Right Ventricular Assist Device Implant Confer a Survival Advantage

ACTION Publication, Publications

Concerns about survival have made biventricular support less common in children. Drawing on 223 pediatric patients in the ACTION registry, this study asked whether the timing of RVAD placement matters. Patients who received both devices in a single operation had better one-year survival, despite being sicker going into surgery.

Does Earlier Right Ventricular Assist Device Implant Confer a Survival Advantage Read More »

Infectious Adverse Events in Pediatric Paracorporeal Ventricular Assist Devices: An Analysis of the Advanced Cardiac Therapies Improving Outcomes Network (ACTION) Registry

ACTION Publication, Publications

This ACTION registry study of 812 children on paracorporeal VADs found that one-third experienced infectious adverse events, which were associated with worse survival. Overlapping device support and smaller body size emerged as independent risk factors for infection.

Infectious Adverse Events in Pediatric Paracorporeal Ventricular Assist Devices: An Analysis of the Advanced Cardiac Therapies Improving Outcomes Network (ACTION) Registry Read More »